Chronic intracerebroventricular (ICV) injection of a VGF peptide named TLQP-21 increased resting energy expenditure and temperature in mice. Furthermore, in mice fed a high-fat diet, the same peptide prevented the increase in body and white adipose tissue (WAT) weight as well as hormonal changes associated with a high-fat regimen.

Rotundifuran is extracted from the fruit of Vitex rotundifolia. Rotundifuran inhibits cell cycle progression and induces apoptosis in human myeloid leukemia cells.

5-TAMRA (5-Carboxytetramethylrhodamine) yields bright, pH-insensitive orange-red fluorescence (approximate excitation/emission maxima ~546/579) with good photostability.